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2007 Awardees

Investigator-Initiated Grant Awardees:

Dr. Angelo All
Johns Hopkins University - Whitaker Biomedical Engineering Institute
"Human Embryonic Stem Cell-Derived Oligodendrocytes and Electrophysiological Studies in a Contusion Model of Spinal Cord Injury in the Rat"

Dr. Jeff Bulte
Johns Hopkins University - School of Medicine
"Human Embryonic Stem Cell-Derived Neurospheres for Treatment of Multiple Sclerosis"

Dr. Curt Civin
Johns Hopkins University - Kimmel Cancer Center
"MicroRNA Regulation of Adult and Embryonic Human Hematopoietic Development"

Dr. William Lederer
University of Maryland, Biotechnology Institute - Medical Biotechnology Center
"Human Mesenchymal Stem Cell Treatment for Heart Damage"

Dr. Lloyd Mitchell
RetroTherapy, LLC
"Preservation of Potentiality in Genetically Altered Stem Cells"

Dr. Hongjun Song
Johns Hopkins University - School of Medicine
"Characterization of Neuronal Potentials of Human Embryonic Stem and Adult Neural Stem Cells"

Dr. Elias Zambidis
Johns Hopkins University - Kimmel Cancer Center
"Human Embryonic Stem Cell Models of Normal and Leukemic Human Stem Cell"

Exploratory Grant Awardees:

Dr. Shyam Biswal
Johns Hopkins University - School of Public Health
"Nrf2 as a Target for Cancer Stem Cell Chemoresistance"

Dr. Srinivasan Chandrasegaran
Johns Hopkins University - School of Public Health
"Targeted Engineering of the Human Genome in Stem Cells"

Dr. Nancy Craig
Johns Hopkins University - School of Medicine
"Genome Engineering of Human Stem Cells for Gene Therapy"

Dr. Shengyun Fang
University of Maryland, Biotechnology Institute - Medical Biotechnology Center
"Ubiquitination-Dependent Regulation of Oct-4 Activity"

Dr. Ricardo Feldman
University of Maryland, Baltimore - School of Medicine
"A Model for Generation of Gaucher-Specific Human Embryonic Stem Cells, and for Reconstitution of Glucocerebrosidase Expression in Human Embryonic Stem Cell-Derived Macrophages"

Dr. Paul Fishman
University of Maryland, Baltimore - School of Medicine
"Transcription Factor Driven Differentiation of Neural Stem Cells"

Dr. Gary Fiskum
University of Maryland, Baltimore - School of Medicine
"Stem Cell Antioxidant Gene Preconditioning for Improved Cell Survival and Neurologic Outcome after Traumatic Brain Injury"

Dr. John Fisher
University of Maryland College Park - School of Engineering
"Human Mesenchymal Stem Cells for Craniofacial Bone Regeneration"

Dr. M. Samir Jafri
University of Maryland, Baltimore - School of Medicine
"A Delivery System for Stem Cells"

Dr. Candace Kerr
Johns Hopkins University - School of Medicine
"Defining Genes Associated with Human Stem Cell Pluripotency and Self-Renewal"

Dr. Hai-Quan Mao
Johns Hopkins University - Whiting School of Engineering
"Engineering an Artificial Neural Stem Cell Niche"

Dr. Andrew McCallion
Johns Hopkins University - School of Medicine
"Illuminating Human Cardiac Development and Disease through Transcriptional Analysis in Differentiating Human Embryonic Stem Cells"

Dr. Guo-li Ming
Johns Hopkins University - Institute for Cell Engineering
"Mechanisms Regulating Self Renewal of Human Embryonic Stem Cells"

Dr. Akhilesh Pandey
Johns Hopkins University - School of Medicine
"Proteomic Characterization of Neural Differentiation in Human Embryonic Stem Cells"

Dr. Adam Puche
University of Maryland, Baltimore - School of Medicine
"Regulating Stem Cell Migration in the Adult Brain"

Dr. Hamid Rabb
Johns Hopkins University - School of Medicine
"Isolation, Expansion and Regenerative Potential of Human Adult Kidney Derived Stem Cells"

Dr. Karen Zeller
Johns Hopkins University - School of Medicine
"Myc's Role in Maintenance and Tumorigenicity of Human Embryonic Stem Cells"

2008 Awardees

Investigator-Initiated Grant Awardees:

Dr. Laure Aurelian
University of Maryland, Baltimore
"Stem cell transplantation is associated with HSV-induced severe skin eruptions"

Dr. Stephen Baylin
University of Maryland, Baltimore
"Genomic and Epigentic Instability of Human Stem Cells Used In Regenerative Medicine"

Dr. Ted M. Dawson
Johns Hopkins University
"Derivation and Characterization of Human Dopamine Neurons Derived from Inducible Pluripotent Stem Cells"

Dr. Valina L. Dawson
Johns Hopkins University
"The novel protein Botch promotes neurogenesis through regulation of the Notch pathway"

Dr. Richard L. Eckert
University of Maryland, Baltimore
"Epidermis-Derived Multipotent Cells for Cell Therapy"

Dr. John T. Iaascs
University of Maryland, Baltimore
"Developing Methods for the Identification and Isolation of Prostate Cancer Stem Cells"

Dr. Dara Kraitchman
Johns Hopkins University
"Magnetic Resonance Imaging (MRI)-Visible Microencapsulation of Allogeneic Mesenchymal Stem Cells for Arteriogenic Therapy in Peripheral Arterial Disease"

Dr. John Laterra
Hugo W. Moser Research Institute at Kennedy Krieger
"Molecular Mechanisms of Tumor-Propagation by Human Glioblastoma Stem Cells"

Dr. Nicholas J. Maragakis
Johns Hopkins University
"Human Astrocyte Progenitor Transplantation for Neuroprotection in a Model of Amyotrophic Lateral Sclerosis (ALS)"

Dr. Jeffrey D. Rothstein
Johns Hopkins University
"Human Astroglial Stem Cells: Combinatorial Drug Discovery Program"

Dr. Elias Zambidis
Johns Hopkins University
"Efficient Generation of Patient Specific Human Embryonic Hemangioblasts"

Exploratory Grant Awardees:

Dr. Maria R. Abraham
Johns Hopkins University
"Molecular engineering of human cardiac-derived progenitor cells and the myocardial micro-environment to improve cardiac regeneration"

Dr. Dmitri Artemov
Johns Hopkins University
"Targeted Imaging and Therapy of Breast Cancer Stem-like Cells"

Dr. Sergi Atamas
University of Maryland, Baltimore
"Bone and Tendon Healing Mechanisms of Mesenchymal Stem Cells and Hematopoetic Progenitors Derived From Human Adult Bone Marrow"

Dr. Ilia V. Baskakov
University of Maryland Biotechnology Institute
"Design of self-assembling peptide scaffold for controlling neural stem cell state and fate"

Dr. Fred Bunz
Johns Hopkins University
"Developing alternative methods for iPS cell generation"

Dr. Chi V. Dang
Johns Hopkins University
"A novel, robust strategy to map human stem cellness transcriptional network"

Dr. Jeniffer H. Elisseeff
Johns Hopkins University
"Adult and embryonic stem cells for cartilage repair and OA"

Dr. Alan D. Friedman
Johns Hopkins University
"Regulation of Human Hematopoietic Stem Cell Proliferation by RUNX1, Notch and Wnt"

Dr. Nicholas Gaiano
Johns Hopkins University
"Exploring the role of NF-κB signaling in human neural stem cells"

Dr. Yoon Young Jang
Johns Hopkins University
"Human Embryonic Stem Cell Transplantation For Liver Regeneration"

Dr. Carol L. Keefer
University of Maryland, College Park
"Mechanical Aspects Of Human Embryonic Stem Cell Differentiation Using Atomic Force Microscopy"

Dr. Candace Kerr
Johns Hopkins University
"MicroRNA analysis of pluripotent stem cells"

Dr. Andre Levenko
Johns Hopkins University
"Control of Human Neural Stem Cell Survival, Proliferation and Differentiation using novel micro and nano fluidic platforms"

Dr. David Litwack
University of Maryland, Baltimore
"Regulation of neuronal differentiation by Nuclear Factor One transcription factors"

Dr. David M. Loeb
Johns Hopkins University
"Regulation Identification and Characterization of the Ewing Sarcoma Stem Cell"

Dr. Stuart Martin
University of Maryland, Baltimore
"Novel therapies to destroy circulating breast tumor stem cells"

Dr. Merryn J. Monteiro
University of Maryland Biotechnology Institute
"Role of ubiquilin in regulating proliferation and differentiation of human stem cells"

Dr. Sarah Netzle-Arnett
University of Maryland, Baltimore
"Targeting Prosurvival Pathways for enhanced stem cell based therapy"

Dr. Martin G. Pomper
Johns Hopkins University
"Stem Cell Probe Discovery via Bioluminescence"

Dr. Yun Qui
University of Maryland, Baltimore
"Regulation of Stemness by Phosphorylation"

Dr. Alfredo Quinones-Hinojosa
Johns Hopkins University
"Human Brain Cancer"

Dr. Venu Raman
Johns Hopkins University
"Characterizing the Role of Twist in the Development of Breast Cancer Stem Cells"

Dr. Linda Resar
Johns Hopkins University
"The Role of HMGA1a in Normal and Leukemic Stem Cells"

Dr. Charles M. Rudin
Johns Hopkins University
"Notch Signaling in Lung Cancer Stem Cells"

Dr. Nitish Thakor
Johns Hopkins University
"The formation of neuromuscular junctions in microfluidic chamber"

Dr. Leslie Tung
Johns Hopkins University
"Antiarrhythmic Properties of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Model of Dysfunctional Cardiac Tissue"

Dr. Piotr Walczak
Johns Hopkins University
"Non-Invasive Imaging and Evaluation of Glial Differentiation and Engraftment of Skin-Derived Pluripotent Stem Cells"

Dr. Katherine Whartenby
Johns Hopkins University
"Gene modification of bone marrow stem cells to generate anti-tumor responses"

Dr. Huakun Xu
University of Maryland, Baltimore
"Stem Cell Delivery via Injectable, Nano-Apatite Scaffolds for Bone Engineering"

Dr. Paul Yarowsky
University of Maryland, Baltimore
"Targeted Therapy for Neurodegenerative Diseases with Magnetically Labeled Stem Cells"

Dr. Srinivasan Yegnasubramanian
Johns Hopkins University
"Epigenetic Characterization of Normal Hematopoietic and Chronic Myeloid Leukemia Stem Cells"

Dr. Stephen Zhan
University of Maryland, Baltimore
"The role of cortactin in EMT and differentiation of human embryonic stem cells"

Fellowship Grant Awardees:

Dr. Jonathan Alder
Johns Hopkins University
"Genetic Rescue of Short Telomere Defect in Hematopietic Stem Cells"

Dr. Michael Bonaguidi
Johns Hopkins University
"Extrinsic Regulation of Adult Human Neural and Cancer Stem Cells in Normal and Disease States"

Dr. Selen Cantania
University of Maryland, Baltimore
"Regulation of Mesenchymal Stem Cell Differntiation by Wnt Signaling: The Role for LRP-1"

Dr. Jessica Carmen
Johns Hopkins University
"NG2 Human Precursor Dysfunction and Neurodegeneration"

Dr. Jon Gerber
Johns Hopkins University
"Characterization and Expansion of Leukemia Stem Cells"

Dr. Hugo Guerrero
Johns Hopkins University
"Role of Slit Proteins in the Migrator Behavior of Brain Tumor Stem Cells"

Dr. Maged Harraz
Johns Hopkins University
"The Role of Human Embrionic Stem Cells and Induced Pluripotent Stem Cells for Cellular Therapy of Parkinson’s Disease"

Dr. Biju Joseph
Johns Hopkins University
"HMGA1 in the Maintenance & Proliferation of Human Embryonic Stem Cells"

Dr. Tarja Juopperi
Johns Hopkins University
"A Comparison of Human Embyonic Stem Cells and Induced Pluripotent Stem Cells for Cellular Therapy of Parkinson’s Disease"

Dr. Vasiliki Machairaki
Johns Hopkins University
"Human Neural Stem Cell-biomatrix Preparations as Tools to Repair Injured Hippocampal Circuits"

Dr. Celine Plachez
University of Maryland, Baltimore
"Role of Metalloproteinases in the Migration of Transplanted Human Stem Cells"

Dr. Marina Pryzhkova
Johns Hopkins University
"Differentiation of Patient-Specific Human Pluripotent Stem Cells"

Dr. Kara Scheibner
University of Maryland, Baltimore
"Regulation and Manipulation of Stem Cell Apoptosis by MicroRNA-27a"

Dr. Farhad Vesuna
Johns Hopkins University
"Involvement of TWIST in Generating Breast Cancer Stem-Like Cells"

Dr. Jizhong Zou
Johns Hopkins University
"Gene Targeting in Human Pluripotent Stem Cells"

2009 Awardees

Investigator-Initiated Grant Awardees:

Dr. Angelo All

Johns Hopkins University

"Stem Cell Therapy after Early Hypothermia in Spinal Cord Injury: Anatomical and Functional Correlates of Recovery”

Dr. Linzhao Cheng

Johns Hopkins University

"Derivation and use of patient-specific iPS cells for modeling acquired blood diseases”

Dr. Valina Dawson

Johns Hopkins University

"Neuroprotective Pathways in iPS Derived Human Neuronal Cultures”

Dr. Ricardo Feldman

University of Maryland, Baltimore

"Generation of patient-specific iPS cells for modeling and treating Gaucher disease”

Dr. Roger Johns

Johns Hopkins University

"A novel stem cell therapy for spinal cord injury-induced chronic neuropathic pain”

Dr. Guo-li Ming

Johns Hopkins University

"Understanding functions of schizophrenia susceptibility genes using pluripotent human stem cells”

Exploratory Grant Awardees:

Dr. Jonathan Auerbach

GlobalStem

"Scale-Up Manufacturing, Authentication, and Banking of Human Pluripotent Stem Cells."

Dr. Alexey Belkin

University of Maryland, Baltimore

"The role of transglutaminase in adhesion-dependent and growth factor-mediated responses of mesenchymal stem cells"

Dr. Michael Betenbaugh

Johns Hopkins University

"A Translational Study to Define Cell Culture Conditions For Human Embryonic Stem Cell Expansion on Collagen"

Dr. Maria Canto-Soler

Johns Hopkins University

"Development of iPS technology for the treatment of retinal degeneration"

Dr. Chunzhang Cao

University of Maryland, Baltimore

"Activated Protein C protects mesenchymal stem cells from ischemia-induced death"

Dr. Curt Civin

University of Maryland, Baltimore

"The Hippo pathway in control of hematopoietic organ size and stemness"

Dr. Anne Comi

Hugo W. Moser Research Institute at Kennedy Krieger

"Human Cord Blood Stem Cell in a Mouse Model of Neonatal Stroke"

Dr. Jenice D'Costa

Virxsys Corporation

"Developing safer methods for induced Pluripotent Stem (iPS) cell generation using Spliceosome-mediated RNA trans-splicing (SMaRTTM) technology"

Dr. Alan Friedman

Johns Hopkins University

"RUNX1 Role and Epigenetics in Development of HSC from Human ES/iPS"

Dr. Da-Wei Gong

University of Maryland, Baltimore

"Novel vector systems to reprogram human adipose stromal vascular cells into insulin-producing cells and transplantable adipocytes"

Dr. Jordan Green

Johns Hopkins University

"Non-Viral Nanoparticles for Creation of Human Induced Pluripotent Stem Cells"

Dr. John Harmon

Johns Hopkins University

"Platform Technology to Promote Angiogenesis and Healing in Burn Wounds Using Hydrogels and Stem Cells"

Dr. Joelle Hillion

Johns Hopkins University

"The Role of HMGA2 in Normal & Leukemic Stem Cells"

Dr. Yoon-Young Jang

Johns Hopkins University

"Functional Isolation of Niche Specific Human Stem Cells"

Dr. Feng Jiang

University of Maryland, Baltimore

"A MicroRNA Signature of Cancer Stem Cell as Prognostic Biomarker for Lung Cancer"

Dr. Mihoko Kai

Johns Hopkins University

"DNA Damage Response in Glioblastoma Stem Cells"

Dr. Mariusz Karbowski

University of Maryland Biotechnology Institute

"Maintenance of Mitochondrial Fusion and Fission as a Critical Factor in Stem cell viability, Differentiation Capacity and Differentiation-induced Mitochondrial Biogenesis"

Dr. Irina Kolosova

Johns Hopkins University

"Role of hypoxia-induced mitogenic factor in regulating proliferation and differentiation of human stem cells"

Dr. Gerard Lutty

Johns Hopkins University

"Progenitor cell based therapies for ocular vasculopathies"

Dr. Hai-Quan Mao

Johns Hopkins University

"Matrix-Assisted Schwann-Cell Differentiation from Human Induced Pluripotent Stem Cells for Peripheral Nerve Regeneration"

Dr. Nicholas Maragakis

Johns Hopkins University

"Development of iPS cells for ALS research"

Dr. Avindra Nath

Johns Hopkins University

"Inflammatory cells and Neuronal Stem Cell Functions: A New Frontier for Therapeutic Stem Cell Transplantation in Neurodegenerative Diseases"

Dr. Sridhar Nimmagadda

Johns Hopkins University

"Brain Tumor Stem Cell Imaging With Radiolabeled Antibodies"

Dr. Elizabeth Powell

University of Maryland, Baltimore

"Ligand presentation directs neural stem cell fate decisions"

Dr. Linda Resar

Johns Hopkins University

"Molecular Pathways Induced by HMGA1 in Embryonic Stem Cells"

Dr. Lewis Romer

Johns Hopkins University

"Harnessing Induced Pluripotent Cells for Pulmonary Microvascular Restitution Using the Focal Adhesion Kinase"

Dr. Michael Shamblott

Hugo W. Moser Research Institute at Kennedy Krieger

"ECM, Integrins and Endocrine differentiation"

Dr. Hong Song

Johns Hopkins University

"Targeting metastatic pancreatic cancer stem cells by alpha particle radiation"

Dr. Karl Womer

Johns Hopkins University

"Immunoregulatory Function of Pancreas Mesenchymal Stem Cells"

Dr. Shuli Xia

Hugo W. Moser Research Institute at Kennedy Krieger

"Differentiation Therapy of Glioblastoma Stem Cells"

Dr. Xuehong Xu

University of Maryland Biotechnology Institute

"P-QD hESC Labeling and Its Application on Cell Transdifferentiation"

Post - Doctoral Fellowship Grant Awardees:

Dr. Julio Altamirano

University of Maryland Biotechnology Institute

"Calcium signaling in cardiac hESC -dervied myocytes and their functional interations with acutely isolated rat venticular myocytes in primary cultures"

Dr. Amy Belton

Johns Hopkins University

"HMGA1 in Intestinal & Colon Cancer Stem Cells"

Dr. Paul Burridge

Johns Hopkins University

"Differentiation of Patient-Specific Pluripotent Human Stem Cells for Treatment of Cardiomyopathy"

Dr. Wen-Chih Cheng

University of Maryland, Baltimore

"The role of Hpo signaling pathway in controlling stemness of hematopoietic stem-progenitor cells"

Dr. Tara Deans

Johns Hopkins University

"Directing Mesenchymal Stem Cell Differentiation By Combining Principles of Synthetic Biology and Materials Science"

Dr. Tomas Garzon-Muvdi

Johns Hopkins University

"Role of Cation-Chloride cotransporters and PDGF in migration of brain tumor stem cells"

Dr. Nini Guo

Johns Hopkins University

"Telomeres and telomerase in pancreatic stem cell maintenance and carcinogenesis"

Dr. Woon Ryong Kim

Johns Hopkins University

"Application of patient-specific induced pluripotent stem cells for understanding and therapy of the Huntington’s disease"

Dr. Ming Jung Kim

University of Maryland, Baltimore

"Interplay of hypoxia-inducible factor-1 (HIF-1) and microRNAs in regulation of human erythropoiesis"

Dr. Ju Young Kim

Johns Hopkins University

"Understanding the function of DISC1 interactome in regulating human neural stem cells and their development"

Dr. Desiree Krebs-Kraft

University of Maryland, Baltimore

"Sex differences in human stem cells:  Implications for endocannabinoids"

Dr. Xingyu Liu

Johns Hopkins University

"Development of ECM-based hydrogel maxtrix with controlled stability to improve the adhension of human induced pluripotent stem cells"

Dr. Ahmed Mohyeldin

Johns Hopkins University

"The role of aerobic glycolysis and hypoxia inducible factor 1 (HIF-1a) in glioma stem cell proliferation and invasion"

Dr. Tea Soon Park

Johns Hopkins University

"Development of Endothelial Progenitors from Human Induced Pluripotent Stem Cells for Vascular Regenerative Therapy"

Dr. Margaret Showel

Johns Hopkins University

"Characterizing and Targeting Acute Lymphocytic Leukemia Stem Cells"

Dr. Guoming Sun

Johns Hopkins University

"Biodegradeable Hydrogel Scaffolds for Vascular Regeneration"

Dr. Jaylyn Waddell

University of Maryland, Baltimore

"Androgens and survival of human neural stem cells"

Dr. Karl Wahlin

Johns Hopkins University

"Induction of human iPS cells towards a photoreceptor-like fate"

Dr. Yi Yang

Johns Hopkins University

"Identify targets of miR-302 in human embryonic stem cells using a quantitative proteomic approach"

Dr. Mingyao Ying

Johns Hopkins University

"Differentiation Therapy Induced by Kruppel-like Factor in Glioblastoma Stem cells"

Dr. Huimei Yu

Johns Hopkins University

"Characterization of Neural Defects of iPSCs from Trisomy Patients"