2012 Awardees

Investigator-Initiated Grant Awardees:

Jeff Bulte

Johns Hopkins University- School of Medicine (JHU)

"Co-Encapsulation of Human Mesenchymal Stem Cells and Islet Cells for Treatment of Type 1 Diabetes"

Ted Dawson

Johns Hopkins University- School of Medicine (JHU)

"Generation and Characterization of Isogenic Parkinson’s Disease and Control iPS Cells"

Jennifer Elisseeff

Johns Hopkins University- School of Medicine (JHU)

In collaboration with Tissue Banks International, Inc. & CIRM

"ECM-Based Materials for Stem Cell Differentiation and Bone Repair"

Dawei Gong

University of Maryland, Balitmore (UMB)

"Towards Modeling Pathogenesis and Treatment of Congenital Generalized Lipodystrophy Using Patient-Specific iPSCs"

Bartley Griffith

University of Maryland, Baltimore (UMB)

"Improving MSC Engraftment in the Ischemic Heart"

Minoru Ko

Elixirgen, LLC

"Generating Human Induced Pluripotent Stem Cells with Less Cancer-Risk"

Gabsang Lee

Johns Hopkins University- School of Medicine (JHU)

In collaboration with Life Technologies, Inc.

"Derivation of Functional Nociceptive Neurons From hESC and Its Application to Pain-Disorder Human iPSC"

Guo-Li Ming

Johns Hopkins University- School of Medicine (JHU)

"Toward Correction of Neurodevelopmental Defects Of Neurons Derived from Patients with Mental Disorders"

Zack Wang

Johns Hopkins University- School of Medicine (JHU)

"Vascular Progenitor Cell Generation from Human Pluripotent Stem Cells (hPSC) for Peripheral Vascular Diseases"

Exploratory Grant Awardees:

Gerald Brandacher

Johns Hopkins University- School of Medicine (JHU)

"Induced Pluripotent Stem Cell (iPS) Derived Schwann Cells to Enhance Functional Recovery Following Nerve Injury and Limb Allotransplantation"

Maria Canto-Soler

Johns Hopkins University- School of Medicine (JHU)

"Development of 3D-Culture Systems of Human iPSC Derived-Retinal Cells for Clinical Applications"

Miroslaw Janowski

Johns Hopkins University- School of Medicine (JHU)

In collaboration with Q Therapeutics, Inc.

"Magnet-Navigated Targeting of Myelin Producing Cells to The Stroke Via Intraventricular Route in a Large Animal Model"

Hongkai Ji

Johns Hopkins School of Public Health (JHSPH)

"Global Prediction of Transcription Factor Binding Sites in Lineage Specific Neuronal Differentiation"

Baktiar Karim

Johns Hopkins University- School of Medicine (JHU)

"CD133: A Master Regulator of Intestinal Differentiation And Stem Cell Regeneration in Crohn's Disease"

Tami Kingsbury

University of Maryland, Baltimore (UMB)

"MicroRNAs and Control of Quiescence and Pluripotency"

Chulan Kwon

Johns Hopkins University- School of Medicine (JHU)

"Membrane Notch Control of Human Cardiovascular Progenitors"

Martin Pomper

Johns Hopkins University- School of Medicine (JHU)

"New ALDH Based Imaging Agents for Stem Cells"

Sivaprakash Ramalingam

Johns Hopkins School of Public Health (JHSPH)

"Functional Correction of hiPSCs with Homozygous Sickle Cell Disease Mutation Using Engineered ZFNs/TALENs"

Antony Rosen

Johns Hopkins University- School of Medicine (JHU)

"Using hESCs to Define Novel Scleroderma Autoantigens in Stem Cells and Vascular Progenitors"

Kara Scheibner

University of Maryland, Baltimore (UMB)

"Regulation of DNA Double Strand Break Repair in Human Hematopoietic Stem Cells by MicroRNAs"

Wenxia Song

University of Maryland College Park (UMCP)

"In Vitro Differentiation of Human Induced Pluripotent Stem Cells Into B-Cells For Modeling Human Diseases"

Joseph Stains

University of Maryland, Baltimore (UMB)

"Using Gap Junctions to Enhance Stem Cell Therapies in Osteoarthritis"

Bhanu Telugu

University of Maryland College Park (UMCP)

"Role of Crucial Oxygen Sensitive Transcription Factor, HIF1A in stemness and in Disease"

Arun Venkatesan

Johns Hopkins University- School of Medicine (JHU)

"Novel Human iPSC-Based Model Of Axon Degeneration In Multiple Sclerosis"

Mingyao Ying

Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (KKI)

"Highly Efficient Conversion of Human Stem Cells to Dopaminergic Neurons by Proneural Transcription Factor Atoh1"

Steven Zhan

University of Maryland, Baltimore (UMB)

Post - Doctoral Fellowship Grant Awardees:

Ola Awad

University of Maryland, Baltimore (UMB)

"Role of Autophagy Dysregulation in the Development of Neurodegeneration Using iPSC Model of Gaucher's Disease"

Amnon Bar-Shir

Johns Hopkins University- School of Medicine (JHU)

"Mri-Based Reporter Genes For Non-Invasive Assessment Of The Fate Of Stem Cell-Seeded Scaffolds"

Su Mi Choi

Johns Hopkins University- School of Medicine (JHU)

In collaboration with Cellomics Technology, LLC

"Patient Specific Stem Cell based In Vitro Model of Liver Cirrhosis"

Christopher Donnelly

Johns Hopkins University- School of Medicine (JHU)

"Development of an Antisense Oligonucleotide Therapeutic Utilizing Stem Cell Derived Patient Astrocytes to Treat ALS and Dementias Caused by C9ORF72 Expanded Hexanucleotide Repeat"

Gabriel Ghiaur

Johns Hopkins University- School of Medicine (JHU)

"Retinoic Acid (RA) Controls Self Renewal and Differentiation of Human Hematopoietic Stem Cells (HSCs)

Pinar Huri

Johns Hopkins University- School of Medicine (JHU)

"Engineering Clinically-Applicable Vascularized Bone Grafts using Adipose-Derived Stem Cells"

Eunchai Kang

Johns Hopkins University- School of Medicine (JHU)

"Modeling Of Major Mental Disorders Using Human Induced Pluripotent Cells Derived From Patients With A Defined Disc1 Mutation"

Chaekyu Kim

Johns Hopkins University- School of Medicine (JHU)

"Small Molecules to Influence Metabolism in Stem Cells and Tissue Formation in Hydrogels"

Changmei Liu

Johns Hopkins University- School of Medicine (JHU)

"Small RNA Regulation Of GSK3 Expression Modulates Human Neural Stem Cells Proliferation and Differentiation"

Georgia Makri

Johns Hopkins University- School of Medicine (JHU)

"Patient-Specific iPSCs for Modeling and Treatment of Rett Syndrome"

Sharyn Rossi

Johns Hopkins University- School of Medicine (JHU)

"Optogenetic Analysis Of Stem Cell Integration Into Forebrain Circuits Following Traumatic Axonal Injury"

Kit Tsang

Johns Hopkins University- School of Medicine (JHU)

"Epigenetic Regulation of Hematopoietic Differentiation from Human Pluripotent Stem Cells"

Yi-Lan Weng

Johns Hopkins University- School of Medicine (JHU)

"Effects of DNA Methylation Reprogramming in Axonal Plasticity and Regeneration"

Yaxue Zeng

Johns Hopkins University- School of Medicine (JHU)

"Characterizing the Role of Active DNA Demethylation in Reprogramming of Human Somatic Cell into Stem Cells"