2009 Awardees

Investigator-Initiated Grant Awardees:

Dr. Angelo All

Johns Hopkins University

"Stem Cell Therapy after Early Hypothermia in Spinal Cord Injury: Anatomical and Functional Correlates of Recovery”

Dr. Linzhao Cheng

Johns Hopkins University

"Derivation and use of patient-specific iPS cells for modeling acquired blood diseases”

Dr. Valina Dawson

Johns Hopkins University

"Neuroprotective Pathways in iPS Derived Human Neuronal Cultures”

Dr. Ricardo Feldman

University of Maryland, Baltimore

"Generation of patient-specific iPS cells for modeling and treating Gaucher disease”

Dr. Roger Johns

Johns Hopkins University

"A novel stem cell therapy for spinal cord injury-induced chronic neuropathic pain”

Dr. Guo-li Ming

Johns Hopkins University

"Understanding functions of schizophrenia susceptibility genes using pluripotent human stem cells”

Exploratory Grant Awardees:

Dr. Jonathan Auerbach

GlobalStem

"Scale-Up Manufacturing, Authentication, and Banking of Human Pluripotent Stem Cells."

Dr. Alexey Belkin

University of Maryland, Baltimore

"The role of transglutaminase in adhesion-dependent and growth factor-mediated responses of mesenchymal stem cells"

Dr. Michael Betenbaugh

Johns Hopkins University

"A Translational Study to Define Cell Culture Conditions For Human Embryonic Stem Cell Expansion on Collagen"

Dr. Maria Canto-Soler

Johns Hopkins University

"Development of iPS technology for the treatment of retinal degeneration"

Dr. Chunzhang Cao

University of Maryland, Baltimore

"Activated Protein C protects mesenchymal stem cells from ischemia-induced death"

Dr. Curt Civin

University of Maryland, Baltimore

"The Hippo pathway in control of hematopoietic organ size and stemness"

Dr. Anne Comi

Hugo W. Moser Research Institute at Kennedy Krieger

"Human Cord Blood Stem Cell in a Mouse Model of Neonatal Stroke"

Jenice D'Costa

Virxsys Corporation

"Developing safer methods for induced Pluripotent Stem (iPS) cell generation using Spliceosome-mediated RNA trans-splicing (SMaRTTM) technology"

Dr. Alan Friedman

Johns Hopkins University

"RUNX1 Role and Epigenetics in Development of HSC from Human ES/iPS"

Dr. Da-Wei Gong

University of Maryland, Baltimore

"Novel vector systems to reprogram human adipose stromal vascular cells into insulin-producing cells and transplantable adipocytes"

Dr. Jordan Green

Johns Hopkins University

"Non-Viral Nanoparticles for Creation of Human Induced Pluripotent Stem Cells"

Dr. John Harmon

Johns Hopkins University

"Platform Technology to Promote Angiogenesis and Healing in Burn Wounds Using Hydrogels and Stem Cells"

Dr. Joelle Hillion

Johns Hopkins University

"The Role of HMGA2 in Normal & Leukemic Stem Cells"

Dr. Yoon-Young Jang

Johns Hopkins University

"Functional Isolation of Niche Specific Human Stem Cells"

Dr. Feng Jiang

University of Maryland, Baltimore

"A MicroRNA Signature of Cancer Stem Cell as Prognostic Biomarker for Lung Cancer"

Dr. Richard Jones

Johns Hopkins University

"The Clinical Significance of Leukemia Stem Cells"

Dr. Mihoko Kai

Johns Hopkins University

"DNA Damage Response in Glioblastoma Stem Cells"

Dr. Mariusz Karbowski

University of Maryland Biotechnology Institute

"Maintenance of Mitochondrial Fusion and Fission as a Critical Factor in Stem cell viability, Differentiation Capacity and Differentiation-induced Mitochondrial Biogenesis"

Dr. Irina Kolosova

Johns Hopkins University

"Role of hypoxia-induced mitogenic factor in regulating proliferation and differentiation of human stem cells"

Dr. Gerard Lutty

Johns Hopkins University

"Progenitor cell based therapies for ocular vasculopathies"

Dr. Hai-Quan Mao

Johns Hopkins University

"Matrix-Assisted Schwann-Cell Differentiation from Human Induced Pluripotent Stem Cells for Peripheral Nerve Regeneration"

Dr. Nicholas Maragakis

Johns Hopkins University

"Development of iPS cells for ALS research"

Dr. Avindra Nath

Johns Hopkins University

"Inflammatory cells and Neuronal Stem Cell Functions: A New Frontier for Therapeutic Stem Cell Transplantation in Neurodegenerative Diseases"

Dr. Sridhar Nimmagadda

Johns Hopkins University

"Brain Tumor Stem Cell Imaging With Radiolabeled Antibodies"

Dr. Elizabeth Powell

University of Maryland, Baltimore

"Ligand presentation directs neural stem cell fate decisions"

Dr. Linda Resar

Johns Hopkins University

"Molecular Pathways Induced by HMGA1 in Embryonic Stem Cells"

Dr. Lewis Romer

Johns Hopkins University

"Harnessing Induced Pluripotent Cells for Pulmonary Microvascular Restitution Using the Focal Adhesion Kinase"

Dr. Michael Shamblott

Hugo W. Moser Research Institute at Kennedy Krieger

"ECM, Integrins and Endocrine differentiation"

Dr. Hong Song

Johns Hopkins University

"Targeting metastatic pancreatic cancer stem cells by alpha particle radiation"

Dr. Karl Womer

Johns Hopkins University

"Immunoregulatory Function of Pancreas Mesenchymal Stem Cells"

Dr. Shuli Xia

Hugo W. Moser Research Institute at Kennedy Krieger

"Differentiation Therapy of Glioblastoma Stem Cells"

Dr. Xuehong Xu

University of Maryland Biotechnology Institute

"P-QD hESC Labeling and Its Application on Cell Transdifferentiation"

Post - Doctoral Fellowship Grant Awardees:

Dr. Julio Altamirano

University of Maryland Biotechnology Institute

"Calcium signaling in cardiac hESC -dervied myocytes and their functional interations with acutely isolated rat venticular myocytes in primary cultures"

Dr. Amy Belton

Johns Hopkins University

"HMGA1 in Intestinal & Colon Cancer Stem Cells"

Dr. Paul Burridge

Johns Hopkins University

"Differentiation of Patient-Specific Pluripotent Human Stem Cells for Treatment of Cardiomyopathy"

Dr. Wen-Chih Cheng

University of Maryland, Baltimore

"The role of Hpo signaling pathway in controlling stemness of hematopoietic stem-progenitor cells"

Dr. Tara Deans

Johns Hopkins University

"Directing Mesenchymal Stem Cell Differentiation By Combining Principles of Synthetic Biology and Materials Science"

Dr. Tomas Garzon-Muvdi

Johns Hopkins University

"Role of Cation-Chloride cotransporters and PDGF in migration of brain tumor stem cells"

Dr. Nini Guo

Johns Hopkins University

"Telomeres and telomerase in pancreatic stem cell maintenance and carcinogenesis"

Dr. Woon Ryong Kim

Johns Hopkins University

"Application of patient-specific induced pluripotent stem cells for understanding and therapy of the Huntington’s disease"

Dr. Ming Jung Kim

University of Maryland, Baltimore

"Interplay of hypoxia-inducible factor-1 (HIF-1) and microRNAs in regulation of human erythropoiesis"

Dr. Ju Young Kim

Johns Hopkins University

"Understanding the function of DISC1 interactome in regulating human neural stem cells and their development"

Dr. Desiree Krebs-Kraft

University of Maryland, Baltimore

"Sex differences in human stem cells:  Implications for endocannabinoids"

Dr. Xingyu Liu

Johns Hopkins University

"Development of ECM-based hydrogel maxtrix with controlled stability to improve the adhension of human induced pluripotent stem cells"

Dr. Ahmed Mohyeldin

Johns Hopkins University

"The role of aerobic glycolysis and hypoxia inducible factor 1 (HIF-1a) in glioma stem cell proliferation and invasion"

Dr. Tea Soon Park

Johns Hopkins University

"Development of Endothelial Progenitors from Human Induced Pluripotent Stem Cells for Vascular Regenerative Therapy"

Dr. Margaret Showel

Johns Hopkins University

"Characterizing and Targeting Acute Lymphocytic Leukemia Stem Cells"

Dr. Guoming Sun

Johns Hopkins University

"Biodegradeable Hydrogel Scaffolds for Vascular Regeneration"

Dr. Jaylyn Waddell

University of Maryland, Baltimore

"Androgens and survival of human neural stem cells"

Dr. Karl Wahlin

Johns Hopkins University

"Induction of human iPS cells towards a photoreceptor-like fate"

Dr. Yi Yang

Johns Hopkins University

"Identify targets of miR-302 in human embryonic stem cells using a quantitative proteomic approach"

Dr. Mingyao Ying

Johns Hopkins University

"Differentiation Therapy Induced by Kruppel-like Factor in Glioblastoma Stem cells"

Dr. Huimei Yu

Johns Hopkins  University

"Characterization of Neural Defects of iPSCs from Trisomy Patients"