Propagenix Inc. (“Engineering personalized solutions for epithelial tissue disease”) is a Rockville, MD-based cell therapy platform technology company providing engineered tissue solutions to address clinical needs in replacing a patient’s own dysfunctional or damaged barrier tissues.

The company’s technology is based on the ability to massively expand and differentiate tissue-resident epithelial stem cells. Applications of this platform technology is directed at meeting the challenge of manufacturing safe, clinical-scale amounts of biologically functional epithelial cells obtained from individual patients. This deliverable is essential for both transplantation of skin, airway, and corneal lining cells as well as in diagnostic applications in oncology and airway disease. The company’s IP is secured with nine issued patents (eight U.S., one Japan) and multiple additional patents forthcoming.

Propagenix’s partners are biopharmaceutical, medical device, life science, and consumer product firms that access company technology via product sales, licensing, and collaborative research agreements. The company has attracted over ten major biopharmaceutical and life sciences firms as clients, including therapeutic-focused deals to access Propagenix technology.

How MSCRF Helped

TEDCO provided a Commercialization Grant to Propagenix through the Maryland Stem Cell Research Fund.  Propagenix was able to generate key application data on their EpiX™ technology for use with cystic fibrosis patient biopsies, for personalized “theratyping” of existing and investigational drugs with the grant funds.